Longevity & Aging
Computation Meets the Biology of Longevity
Lithium's NF-kB dependent upregulation of klotho in human cardiac fibroblasts, GLP-1 therapy's sarcopenia problem, and a new retrieval alignment framework for drug design share a single underlying problem: the molecular context the biology operates in determines whether any intervention reaches its intended target.
klothoNF-kBmitochondrial dynamicsGLP-1